Invention Grant
- Patent Title: Solid dosage forms comprising an enteric coating with accelerated drug release
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Application No.: US13603984Application Date: 2012-09-05
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Publication No.: US10537530B2Publication Date: 2020-01-21
- Inventor: Fang Liu , Abdul W. Basit , Rosario Lizio , Hans-Ulrich Petereit , Christian Meier , Michael Damm
- Applicant: Fang Liu , Abdul W. Basit , Rosario Lizio , Hans-Ulrich Petereit , Christian Meier , Michael Damm
- Applicant Address: DE Essen
- Assignee: Evonik Operations GmbH
- Current Assignee: Evonik Operations GmbH
- Current Assignee Address: DE Essen
- Agency: Grüneberg and Meyers PLLC
- Main IPC: A61K9/50
- IPC: A61K9/50

Abstract:
The invention provides a gastric resistant, enteric-coated solid dosage form including a core containing a pharmaceutically active ingredient, an inner coating for the core, and an outer enteric coating. The inner coating comprises an anionic polymeric material or a water-soluble neutral polymeric material, and further comprises a water soluble inorganic salt which is not a carbonate or bicarbonates. The outer enteric coating comprises an anionic polymeric material which is less neutralized than the polymeric material comprising the inner coating and disintegrates rapidly at a pH of 5.5 to 7.0 upon entering the small intestine.
Public/Granted literature
- US20130058986A1 SOLID DOSAGE FORMS COMPRISING AN ENTERIC COATING WITH ACCELERATED DRUG RELEASE Public/Granted day:2013-03-07
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