Invention Grant
- Patent Title: Crystals of azabicyclic compound
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Application No.: US15572398Application Date: 2016-05-11
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Publication No.: US10526324B2Publication Date: 2020-01-07
- Inventor: Takao Uno
- Applicant: TAIHO PHARMACEUTICAL CO., LTD.
- Applicant Address: JP Chiyoda-ku
- Assignee: TAIHO PHARMACEUTICAL CO., LTD.
- Current Assignee: TAIHO PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Chiyoda-ku
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2015-097521 20150512
- International Application: PCT/JP2016/063989 WO 20160511
- International Announcement: WO2016/181990 WO 20161117
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/4439 ; A61P35/00

Abstract:
Provided are crystals of 3-ethyl-4-{3-isopropyl-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl}benzamide which are stable and show excellent oral absorbability.The crystals are Form II crystals of 3-ethyl-4-{3-isopropyl-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl}benzamide showing an X-ray powder diffraction spectrum having at least three characteristic diffraction peaks at angles (2θ±0.2°) selected from the group consisting of 7.7°, 8.0°, 11.1°, 12.5°, 12.9°, 15.2°, 15.8°, 17.2°, 19.0°, 22.5°, 26.1°, and 27.4°.
Public/Granted literature
- US20180148443A1 CRYSTALS OF AZABICYCLIC COMPOUND Public/Granted day:2018-05-31
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