The present disclosure relates to initiating remediation of security risks on an endpoint system based on updated reputation data. According to one embodiment, a reputation service receives a request, from a first endpoint system, for reputation data about an object. A reputation service transmits, in response to the request, data indicating a current reputation of the object. The reputation service determines that the object presents a security risk and updates reputation data associated with the object to indicate that the object presents a security risk. Upon updating the reputation data, the reputation system transmits, to the first endpoint system, updated reputation data associated with the object and instructions to remedy the security risk.