A compressor wheel of a fluid compression device includes a wheel part, a shaft part and a plurality of connection parts. The wheel part includes a main body formed with a through hole, and a plurality of blades protruded from an outer side of the main body. The shaft part is accommodated in the through hole and configured to connect to a rotor shaft. The plurality of connection parts is connected between an inner side of the main body and the shaft part. Wherein, a fluid passage is formed between the inner side of the main body and the shaft part to allow fluid to flow to a rear side of the compressor wheel from a front side of the compressor wheel via the fluid passage.