Invention Grant
- Patent Title: Polynucleotide probe, method for detecting a target nucleic acid by using the same and kit comprising the same
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Application No.: US15870336Application Date: 2018-01-12
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Publication No.: US10400289B2Publication Date: 2019-09-03
- Inventor: Ja-An A. Ho , Amily F. Jou , Yen-Chuan Ou , Shian-Shiang Wang , Itamar Willner , Shih-Lan Hsu
- Applicant: National Taiwan University
- Applicant Address: TW Taipei
- Assignee: National Taiwan University
- Current Assignee: National Taiwan University
- Current Assignee Address: TW Taipei
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Peter F. Corless; Joohee Lee
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6886 ; C12Q1/6816
Abstract:
The present invention provides a method for detecting a target nucleic acid that comprises a step of providing a sample; contacting the sample with a polynucleotide probe comprising a first sequence and a second sequence complementary to the target nucleic acid; and adding a nuclease for cleaving the second sequence of the polynucleotide probe. The present invention further provides a polynucleotide probe for detecting a target nucleic acid that comprises a first sequence and a second sequence complementary to the target nucleic acid. Moreover, the present invention provides a kit for detecting a target nucleic acid.
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