Invention Grant
- Patent Title: Compositions and methods for inhibiting expression of the ALAS1 gene
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Application No.: US15457725Application Date: 2017-03-13
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Publication No.: US10400239B2Publication Date: 2019-09-03
- Inventor: Brian Bettencourt , Kevin Fitzgerald , William Querbes , Robert J. Desnick , Makiko Yasuda
- Applicant: ALNYLAM PHARMACEUTICALS, INC. , ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Applicant Address: US MA Cambridge US NY New York
- Assignee: ALNYLAM PHARMACEUTICALS, INC.,ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Current Assignee: ALNYLAM PHARMACEUTICALS, INC.,ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Current Assignee Address: US MA Cambridge US NY New York
- Agency: Lando & Anastasi, LLP
- Main IPC: A61K31/713
- IPC: A61K31/713 ; C12N15/113

Abstract:
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ALAS1 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of ALAS1.
Public/Granted literature
- US20180037886A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE Public/Granted day:2018-02-08
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