Invention Grant
- Patent Title: Mutant CsgG pores
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Application No.: US15507947Application Date: 2015-09-01
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Publication No.: US10400014B2Publication Date: 2019-09-03
- Inventor: Stefan Howorka , Han Remaut , Lakmal Jayasinghe , Elizabeth Jayne Wallace , James Anthony Clarke , Richard George Hambley , Jonathan Bankes Pugh
- Applicant: Oxford Nanopore Technologies Ltd. , VIB VZW , Vrije Universiteit Brussel
- Applicant Address: GB Oxford BE Ghent BE Brussels
- Assignee: Oxford Nanopore Technologies Ltd.,VIB VZW,Vrije Universiteit Brussel
- Current Assignee: Oxford Nanopore Technologies Ltd.,VIB VZW,Vrije Universiteit Brussel
- Current Assignee Address: GB Oxford BE Ghent BE Brussels
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: GB1415455.3 20140901; GB1422079.2 20141211; GB1506489.2 20150416; GB1506754.9 20150421; GB1508287.8 20150514; GB1511203.0 20150625; GB1515240.8 20150827
- International Application: PCT/EP2015/069965 WO 20150901
- International Announcement: WO2016/034591 WO 20160310
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07K14/245 ; C12Q1/6869 ; C12Q1/6874 ; G01N27/447
Abstract:
The invention relates to mutant forms of the outer membrane-located lipoprotein CsgG, in particular, modifications at one or more of positions Tyr51; Asn55; and Phe56. The invention also relates to analyte detection and characterisation using said mutant CsgG.
Public/Granted literature
- US20180148481A2 MUTANT CSGG PORES Public/Granted day:2018-05-31
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