Devices, systems, and methods for controlling acquisition of a signal representing a physiological measurement are described herein. An example device comprises: an input for receiving the signal in digital form, wherein the signal has been acquired by means of at least one electrode without galvanic contact between the electrode and the living being and has been processed by circuitry for acquisition of the signal in analog domain to refine the signal before the signal is converted from analog to digital domain; an adaptation decision module, being configured to determine whether a measure of signal quality indicates that an adaptation of the circuitry for acquisition of the signal in analog domain is beneficial for the robustness of the system and/or the quality of the obtained signals; wherein the adaptation decision module, is arranged to output a control signal for controlling a parameter affecting amplifier saturation in processing of the signal.