Disclosed are various embodiments for determining whether food in a refrigerator has spoiled. An application executing on a computing device receives an identification of a food item located in a compartment of the refrigerator. The application then receives a chemical sensor reading from the refrigerator, wherein the chemical sensor reading represents a measured amount of a chemical associated with spoilage of the food item. Subsequently, the application determines that the measured amount of the chemical associated with spoilage of the food item exceeds a threshold amount of the chemical associated with spoilage of the food item. Finally, the application sends a notification to the client device, the notification comprising an indication that the food item is spoiled.