The disclosed computer-implemented method for improving the efficiency of point-in-time representations of databases may include (1) identifying a database that includes (A) one or more utilized storage locations that store substantive data and (B) one or more empty storage locations that are not currently storing any substantive data, (2) creating a point-in-time representation of the database by (A) identifying the empty storage locations and (B) flagging the empty storage locations in connection with the point-in-time representation of the database, (3) detecting a request to write certain substantive data to at least one of the empty storage locations, and then in response to detecting the request, (4) satisfying the request while refraining from performing a copy-on-write operation on the empty storage location due at least in part to the empty storage location not currently storing any substantive data. Various other methods, systems, and computer-readable media are also disclosed.