Invention Grant
- Patent Title: Composition containing active components of Dracocephalum moldavica L. against myocardial ischemia-reperfusion injury
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Application No.: US15531763Application Date: 2015-03-06
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Publication No.: US10369165B2Publication Date: 2019-08-06
- Inventor: Jing Shang , Dongsheng Yu , Youqing Tian , Huali Wu , Lin Ding , Jun Liu
- Applicant: Nanjing Ruiying Runze Biopharmaceutical Technology Co., Inc.
- Applicant Address: CN Nanjing, Jiangsu
- Assignee: NANJING RUIYING RUNZE BIOPHARMACEUTICAL TECHNOLOGY CO., INC.
- Current Assignee: NANJING RUIYING RUNZE BIOPHARMACEUTICAL TECHNOLOGY CO., INC.
- Current Assignee Address: CN Nanjing, Jiangsu
- Agency: Pearne & Gordon LLP
- Priority: CN201410724953 20141203
- International Application: PCT/CN2015/073822 WO 20150306
- International Announcement: WO2016/086543 WO 20160609
- Main IPC: A61K36/53
- IPC: A61K36/53 ; A61K31/352 ; A61K31/7048
Abstract:
Disclosed is a composition containing active components of Dracocephalum moldavica L. against myocardial ischemia-reperfusion injury (MIRI). The composition consists of active components and a pharmaceutically acceptable carrier, wherein the active components comprise luteolin, kaempferol and luteolin-7-O-glucoside. Pharmacodynamic experiments show that these three components can be combined together to synergistically treat myocardial ischemia-reperfusion injury.
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