Invention Grant
- Patent Title: Reactive antibacterial compound and preparation method thereof
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Application No.: US15549162Application Date: 2015-09-18
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Publication No.: US10368544B2Publication Date: 2019-08-06
- Inventor: Shiguo Chen , Lingjun Yuan
- Applicant: Shenzhen University
- Applicant Address: CN Shenzhen
- Assignee: SHENZHEN UNIVERSITY
- Current Assignee: SHENZHEN UNIVERSITY
- Current Assignee Address: CN Shenzhen
- Agency: Metis IP LLC
- Priority: WOPCT/CN2015/072439 20150206
- International Application: PCT/CN2015/090059 WO 20150918
- International Announcement: WO2016/123987 WO 20160811
- Main IPC: C07D213/30
- IPC: C07D213/30 ; C07D213/75 ; A01N33/12 ; D06M13/463 ; D06M13/477 ; A01N27/00 ; A01N57/16 ; C07C211/62 ; C07C271/20 ; C07C271/28 ; C07C275/24 ; C07C275/26 ; C07C309/14 ; C07F9/09 ; A01N47/12 ; A01N47/18 ; A01N47/20 ; A01N47/28 ; A01N47/30 ; A01N57/12 ; D06M13/256 ; D06M13/292 ; D06M13/402 ; D06M13/432 ; D06M13/467 ; D06M16/00

Abstract:
A reactive antibacterial compound is represented by formula (I) or (II): wherein R1 represents OCN-L-NHCOOR′, OCN-L-NHCONHR′, OCN-L-NHCOSR′, OCN-L-COOR′, or OCN-L-COONHR′. G1 represents OCN-M-NHCOOG′, OCN-M-NHCONHG′, OCN-M-NHCOSG′, OCN-M-COOG′, or OCN-M-COONHG′. L, M, R′ and G′ independently for each occurrence represent divalent alkyl and cycloalkyl having from 1 to 18 carbon atoms, optionally substituted by up to 18 heteroatoms. R4 and G4 independently for each occurrence represent a divalent alkyl and cycloalkyl having from 1 to 18 carbon atoms, optionally substituted by up to 18 heteroatoms. G2 and G3 independently for each occurrence represent —H, —F, —Cl, —Br, —I, —OCH3, —OCH2CH3, —OPr, —CN, —SCN, —NO, —NO2, a monovalent unsubstituted or substituted alkyl, cycloalkyl, or aryl having from 1 to 7 carbon atoms. Z and X independently for each occurrence represent —COO, —SO3, or —OPO2OR5. R5 represents a monovalent unsubstituted or substituted alkyl, cycloalkyl, or aryl having from 1 to 6 carbon atoms.
Public/Granted literature
- US20180092356A1 REACTIVE ANTIBACTERIAL COMPOUND AND PREPARATION METHOD THEREOF Public/Granted day:2018-04-05
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