Invention Grant
- Patent Title: Method for obtaining thin fibril collagen by contacting native collagen with an antibody
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Application No.: US15257089Application Date: 2016-09-06
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Publication No.: US10336814B2Publication Date: 2019-07-02
- Inventor: Joseph Orgel , Olga Antipova
- Applicant: MATRIX ODYSSEY, LLC
- Applicant Address: US IL Northbrook
- Assignee: MATRIX ODYSSEY, LLC
- Current Assignee: MATRIX ODYSSEY, LLC
- Current Assignee Address: US IL Northbrook
- Agency: K&L Gates LLP
- Main IPC: C07K14/78
- IPC: C07K14/78 ; G01N33/68 ; A61L27/24 ; C07K1/14

Abstract:
A collagen material having a form of thin fibrils generally free of fibril-bundling proteogylcan interactions, and a method for providing the thin fibril collagen material from native collagen fibers. The method uses proteoglycan antibodies to disassociate the proteoglycan interactions in bundled collagen fibrils to provide the constituent fibrils. The process can be used as a model for arthritis and the resulting fibrils can be used to form new extracellular matrix biomaterials and new tissues.
Public/Granted literature
- US20160368968A1 METHOD FOR OBTAINING THIN FIBRIL COLLAGEN BY CONTACTING NATIVE COLLAGEN WITH AN ANTIBODY Public/Granted day:2016-12-22
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