Invention Grant
- Patent Title: Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid
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Application No.: US15869499Application Date: 2018-01-12
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Publication No.: US10336758B2Publication Date: 2019-07-02
- Inventor: Rudolf Moser , Viola Groehn , Thomas Egger , Thomas Ammann
- Applicant: MERCK & CIE
- Applicant Address: CH Schaffausen
- Assignee: MERCK & CIE
- Current Assignee: MERCK & CIE
- Current Assignee Address: CH Schaffausen
- Agency: Millen White Zelano and Branigan, PC
- Agent Csaba Henter
- Main IPC: C07D475/12
- IPC: C07D475/12 ; C07D475/04 ; A61K31/519 ; A61K9/08 ; A61K9/19 ; A61K9/00
Abstract:
The invention is directed towards stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid and its hemisulfate salt as well as pharmaceutical compositions and uses thereof in therapy, preferably chemotherapy.
Public/Granted literature
- US20180134711A1 New stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid Public/Granted day:2018-05-17
Information query
