Invention Grant
- Patent Title: Inhibitors of ACK1/TNK2 tyrosine kinase
-
Application No.: US15748214Application Date: 2016-08-02
-
Publication No.: US10336734B2Publication Date: 2019-07-02
- Inventor: Nupam P. Mahajan , Kiran N. Mahajan , Nicholas J. Lawrence , Harshani R. Lawrence
- Applicant: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
- Applicant Address: US FL Tampa
- Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.
- Current Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.
- Current Assignee Address: US FL Tampa
- Agency: Meunier Carlin & Curfman LLC
- International Application: PCT/US2016/045096 WO 20160802
- International Announcement: WO2017/023899 WO 20170209
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D405/12 ; C07D403/12 ; C07D405/14 ; C07D401/12 ; C07D239/48 ; A61P35/00
Abstract:
Described are cancer therapies and anti-cancer compounds. In particular, disclosed are inhibitors of ACK1 tyrosine kinase and their use in the treatment of cancer. Methods of screening for new ACK1 tyrosine kinase inhibitors are also disclosed. In specific example, compound having Formula I are disclosed.
Public/Granted literature
- US20180215738A1 INHIBITORS OF ACK1/TNK2 TYROSINE KINASE Public/Granted day:2018-08-02
Information query
IPC分类:
