Invention Grant
- Patent Title: Injectable solution at pH 7 comprising at least one basal insulin the pi of which is between 5.8 and 8.5 and a substituted co-polyamino acid
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Application No.: US14922663Application Date: 2015-10-26
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Publication No.: US10335489B2Publication Date: 2019-07-02
- Inventor: Olivier Soula
- Applicant: ADOCIA
- Applicant Address: FR Lyons
- Assignee: ADOCIA
- Current Assignee: ADOCIA
- Current Assignee Address: FR Lyons
- Agency: Oliff PLC
- Priority: FR1250223 20120109; FR1250224 20120109
- Main IPC: A61K38/28
- IPC: A61K38/28 ; A61K47/42 ; A61K47/34 ; A61K38/26 ; A61K9/00 ; A61K45/06 ; A61K47/30 ; A61K9/08 ; A61K38/22
Abstract:
A composition in the form of an injectable aqueous solution, the pH of which is between 6.0 and 8.0, including at least (a) a basal insulin, the isoelectric point pI of which is between 5.8 and 8.5; and (b) a co-polyamino acid bearing carboxylate charges and substituted with hydrophobic radicals. In one embodiment, the compositions also include a prandial insulin and/or a gut hormone.
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