Invention Grant
- Patent Title: Methods of treating cancer patients with farnesyltransferase inhibitors
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Application No.: US15844478Application Date: 2017-12-15
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Publication No.: US10335404B2Publication Date: 2019-07-02
- Inventor: Antonio Gualberto , Catherine Rose Scholz
- Applicant: Kura Oncology, Inc.
- Applicant Address: US CA San Diego
- Assignee: Kura Oncology, Inc.
- Current Assignee: Kura Oncology, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Jones Day
- Main IPC: A61K45/06
- IPC: A61K45/06 ; C12Q1/6886 ; A61K31/4709
Abstract:
The present invention relates to the field of molecular biology and cancer biology. Specifically, the present invention relates to methods of treating a subject with a farnesyltransferase inhibitor (FTI) that include determining whether the subject is likely to be responsive to the FTI treatment based on genotyping and expression profiling of certain immunological genes and RAS mutation status in the subject.
Public/Granted literature
- US20180092903A1 METHODS OF TREATING CANCER PATIENTS WITH FARNESYLTRANSFERASE INHIBITORS Public/Granted day:2018-04-05
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