A hemostasis instrument for actively stopping the bleeding, in particular after an open, laparoscopic, or endoscopic operation on a patient, having several hemostasis components. The hemostasis instrument has at least the following hemostasis components: a thermal hemostasis device for tissue coagulation by producing a temperature above the coagulation temperature of biological tissue by means of a coagulation electrode; a biochemical hemostasis device for producing a silent electric discharge by means of at least one discharge electrode, and an insulating device, wherein the insulating device is arranged between the discharge electrode and the tissue to be treated; a supplying device for supplying substances that influence blood clotting to the tissue to be treated; and a supply device for supplying noble gas to the tissue to be treated.