A grain management system can condition a grain mass held in grain storage equipment using environmental inputs, varietal inputs, nutrient inputs, and/or characteristic inputs. The inputs can provide a customized grain conditioning strategy or program to maintain nutritional attributes of the grain mass and/or prevent overdrying, mold, decomposition, or other spoilage of the grain mass. The inputs can be entered by a user or automatically detected or entered based on present or historical data associated with the grain or grain conditioning equipment.