Systems and methods for transpositional modulation and demodulation are provided. One such method for generating a signal includes the steps of providing a look-up table having a plurality of quarter-cycle waveforms, each of said quarter-cycle waveforms associated with a respective input level; receiving an input signal; and outputting quarter-cycle waveforms associated with levels of the received input signal. Systems for transpositional modulation are also provided. One such system for generating a signal includes a look-up table having a plurality of quarter-cycle waveforms. Each of the quarter-cycle waveforms are associated with a respective input level, and the look-up table is configured to receive an input signal, and output quarter-cycle waveforms associated with levels of the received input signal.