Embodiments described herein enable the transmission of infrared (IR) signals via an AV cable containing a plurality of signal lines. In embodiments, an IR receiver, and IR emitter, and/or logic circuitry may be integrated within an AV cable (e.g., an HDMI cable) to enable transmitting signals from an IR remote control device to a media device that may be located behind a physical obstruction through which IR signals are unable to pass. By utilizing one or more signal lines of an AV cable to transmit IR signals, existing AV communication protocols may continue to be utilized in a user's home entertainment system. In this manner, a user may be able to locate one or more media devices (e.g., home entertainment devices) in a physically remote location, such as in a cabinet or closet, without sacrificing any IR signaling functionality.