A display screen, a touch pen and a display module are disclosed. The display screen includes a frame, a touch display panel, a controller and a plurality of sound wave detectors; the plurality of sound wave detectors are disposed at different positions on the frame and at the same side of frame as an operating surface of the touch display panel. Sound wave detector detects sound wave signals sent by sound wave emission sources and sends the detected sound wave signals to the controller; the touch display panel detects electromagnetic signals sent by electromagnetic generators and sends them to the controller; the controller determines actual touch positions of a plurality of touch pens on the touch display panel based on the electromagnetic signals and sound wave signals emitted by sound wave emission sources of the touch pens to achieve accurate positioning.