The disclosure relates to a syringe assembly and a syringing method of using the same. The syringe assembly comprises an ultrasonic element, a guide tube and a syringe. The ultrasonic element is used to generate an ultrasonic signal and receive a reflection of the ultrasonic signal. The guide tube comprises a first connecting terminal and a second connecting terminal. The syringe and the guide tube are connected with each other via the second connecting terminal. The syringe assembly according to the present disclosure is able to perform sampling, liquid level detection, clog detection, and the liquid volume detection.