Invention Grant
- Patent Title: Method of treating heterotopic ossification
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Application No.: US15373959Application Date: 2016-12-09
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Publication No.: US10278982B2Publication Date: 2019-05-07
- Inventor: Benjamin Levi , Shailesh Agarwal
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A61K31/198
- IPC: A61K31/198 ; A61K31/436 ; A61K31/7048

Abstract:
The invention provides a method of treating heterotopic ossification in a subject in need thereof. The method comprises administering a hypoxia inducible factor-1α (Hif-1α) inhibitor to the subject. In various embodiments, the Hif-1α inhibitor is PX-478, rapamycin, or digoxin.
Public/Granted literature
- US20170182079A1 METHOD OF TREATING HETEROTOPIC OSSIFICATION Public/Granted day:2017-06-29
Information query
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