A noise cancellation device includes a voice receiving module, a distance measuring module, a noise cancellation module and a speaker module. The voice receiving module is configured to receive a noise. The distance measuring module is configured to send a distance measuring signal to an object, and calculate distance information of the object according to a reflected distance measuring signal reflected by the object. The noise cancellation module is connected to the voice receiving module and the distance measuring module, and is configured to generate a reverse phase signal of the noise according to the noise. The speaker module is connected to the noise cancellation module, and is configured to generate an anti-noise according the reverse phase signal, and sound the anti-noise according to the distance information.