A method of configuring a Universal Serial Bus (USB) connection between a first and second devices, the USB connection comprising a plurality of data channels, each having a pair of signal links, each signal link including a port at either end of the connection, and a signal wire formed of one or more physical wires extending between corresponding ports. Each of the signal links are configured with a first direction for transmission of data. The first direction is determined based on an initial required data transmission capacity in each direction between the first and second devices. Thereafter, depending on required capacity in the different directions, a selection is made which of the signal links should change their direction of transmission from the first direction to a second direction and a redirection signal is sent to each of the selected signal links to cause the change in direction of transmission.