Invention Grant
- Patent Title: Assay and method for quantitating carbonic anhydrase activity and assessing red blood hemolysis
-
Application No.: US15174445Application Date: 2016-06-06
-
Publication No.: US10246733B2Publication Date: 2019-04-02
- Inventor: Ryan R. Geyer , Pan Zhao , Mark D. Parker , Walter F. Boron
- Applicant: CASE WESTERN RESERVE UNIVERSITY
- Applicant Address: US OH Cleveland
- Assignee: CASE WESTERN UNIVERSITY
- Current Assignee: CASE WESTERN UNIVERSITY
- Current Assignee Address: US OH Cleveland
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- Main IPC: C12Q1/527
- IPC: C12Q1/527
Abstract:
A method and assay for using carbonic anhydrase (CA), particularly CA-I or CA-II, as a biomarker of hemolysis. The method and assay detect hemolysis by determining a percentage erythrocyte hemolysis in a specimen or sample of blood based upon quantification of carbonic anhydrase present in the extracellular portion of the blood. The method and test serve to optimize therapeutic efficacy for treatments of hemolysis.
Public/Granted literature
- US20160355867A1 ASSAY AND METHOD FOR QUANTITATING CARBONIC ANHYDRASE ACTIVITY AND ASSESSING RED BLOOD HEMOLYSIS Public/Granted day:2016-12-08
Information query
