Invention Grant
- Patent Title: TMPRSS6 iRNA compositions and methods of use thereof
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Application No.: US15603560Application Date: 2017-05-24
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Publication No.: US10246713B2Publication Date: 2019-04-02
- Inventor: James Butler , Martin Maier , Kevin Fitzgerald , Shannon Fishman , Donald Foster , Vasant Jadhav , Stuart Milstein
- Applicant: Alnylam Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- Agent Maria Laccotripe Zacharakis; Deborah L. Nagle
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02 ; C12N15/113 ; A61K31/713 ; A61K45/06
Abstract:
The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the TMPRSS6 gene, and methods of using such RNAi agents to inhibit expression of TMPRSS6 and methods of treating subjects having a TMPRSS6 associated disorder, e.g., an iron overload associated disorder, such as β-thalassemia or hemochromatosis.
Public/Granted literature
- US20170362594A1 TMPRSS6 iRNA COMPOSITIONS AND METHODS OF USE THEREOF Public/Granted day:2017-12-21
Information query
