Invention Grant
- Patent Title: Antibodies, compounds and derivatives thereof for use in the treatment of male infertility
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Application No.: US14909701Application Date: 2014-08-04
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Publication No.: US10246513B2Publication Date: 2019-04-02
- Inventor: Martin Blomberg Jensen
- Applicant: Rigshospitalet Copenhagen University Hospital
- Applicant Address: DK Copenhagen Ø
- Assignee: RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL
- Current Assignee: RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITAL
- Current Assignee Address: DK Copenhagen Ø
- Agency: Knobbe, Martens, Olson & Bear LLP
- Priority: EP13179609 20130807
- International Application: PCT/DK2014/050235 WO 20140804
- International Announcement: WO2015/018421 WO 20150212
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K16/00 ; A61K38/00 ; C07K16/28 ; A61K39/395 ; A61K38/17
Abstract:
The present invention relates to antagonists or inhibitors, which bind selectively to RANKL/OPGbp and regulate the interaction between RANKL/OPGbp and RANK/OPG. In particular, the present invention relates to an antibody or antigen binding domain, fragment or derivative thereof, immunoreactive with a RANKL/OPGbppeptide for use in the treatment, prevention or alleviation of male infertility or reduced male fertility such as oligospermia or azospermia.
Public/Granted literature
- US20160168252A1 ANTIBODIES, COMPOUNDS AND DERIVATIVES THEREOF FOR USE IN THE TREATMENT OF MALE INFERTILITY Public/Granted day:2016-06-16
Information query
