A method for operating a brake system for motor vehicles comprises in a normal control mode of the system, a displacement of a piston for a pressure supply device is terminated, and inlet valves of the wheel brakes are closed in the event of a specified brake condition. The normal control mode is switched to a special control mode in the event of a specified condition for the pressure supply device. In the event of the specified brake condition in the special control mode, a displacement of the piston of the pressure supply device is terminated by outputting an actuation signal to the pressure supply device, and for at least one selected wheel brake, the corresponding inlet valve is kept open and the corresponding outlet valve is opened at least temporarily while the inlet valves of the remaining wheel brakes are closed.