Invention Grant
- Patent Title: Composition having dye and conjugate of polyethyleneglycol and additive and contrast agent for photoacoustic imaging having the same
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Application No.: US14845592Application Date: 2015-09-04
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Publication No.: US10245329B2Publication Date: 2019-04-02
- Inventor: Tatsuki Fukui , Atsushi Takahashi , Daisuke Sasaguri , Kouichi Kato , Fumiko Tomatsu , Keigo Mizusawa
- Applicant: CANON KABUSHIKI KAISHA
- Applicant Address: JP Tokyo
- Assignee: CANON KABUSHIKI KAISHA
- Current Assignee: CANON KABUSHIKI KAISHA
- Current Assignee Address: JP Tokyo
- Agency: Venable LLP
- Priority: JP2014-181970 20140908; JP2015-172525 20150902
- Main IPC: A61B5/00
- IPC: A61B5/00 ; A61B8/00 ; A61B10/00 ; A61K49/22 ; A61K49/00

Abstract:
The present invention provides contrast agents for photoacoustic imaging which exhibit high degrees of accumulation in tumor and low degrees of retention in the blood and can be administered into the blood. The contrast agents for photoacoustic imaging include a conjugate of a dye and a polyethyleneglycol represented by Formula (1), (5), (6), or (7) and an additive represented by Formula (301).
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