Invention Grant
- Patent Title: Immunological reagents and uses therefor
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Application No.: US15300023Application Date: 2015-04-01
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Publication No.: US10245262B2Publication Date: 2019-04-02
- Inventor: Alexandra Jane Corbett , James McCluskey , Lars Kjer-Nielsen , Zhenjun Chen , Jamie Rossjohn , Onisha Patel , Richard William Birkinshaw , Sidonia Barbara Guiomar Eckle , David Paul Fairlie , Ligong Liu , Jeffrey Yam Wing Mak
- Applicant: THE UNIVERSITY OF QUEENSLAND , Monash University , THE UNIVERSITY OF MELBOURNE
- Applicant Address: AU St. Lucia AU Clayton AU Victoria
- Assignee: The University of Queensland,Monash University,The University of Melbourne
- Current Assignee: The University of Queensland,Monash University,The University of Melbourne
- Current Assignee Address: AU St. Lucia AU Clayton AU Victoria
- Agency: McCarter & English, LLP
- Agent Maria Laccotripe Zacharakis
- Priority: AU2014901185 20140401; AU2014901186 20140401
- International Application: PCT/AU2015/050148 WO 20150401
- International Announcement: WO2015/149130 WO 20151008
- Main IPC: C07D239/54
- IPC: C07D239/54 ; A61K31/513 ; C07D239/545 ; C07K14/74 ; C07D239/60 ; G01N33/569 ; A61K47/55 ; A61K47/64 ; A61K38/00
Abstract:
The present invention provides ligands which bind to MR1, some of which induce MR1 to bind to MAIT cells thereby activating or inhibiting MAIT cell activation.
Public/Granted literature
- US20170209442A1 IMMUNOLOGICAL REAGENTS AND USES THEREFOR Public/Granted day:2017-07-27
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