Invention Grant
- Patent Title: Pulmonary delivery of mRNA to non-lung target cells
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Application No.: US14406504Application Date: 2013-06-07
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Publication No.: US10245229B2Publication Date: 2019-04-02
- Inventor: Michael Heartlein , Braydon Charles Guild , Frank DeRosa , Carsten Rudolph , Christian Plank
- Applicant: Shire Human Genetic Therapies, Inc. , Ethris GmbH
- Applicant Address: US MA Lexington DE Martinsried
- Assignee: Translate Bio, Inc.,Ethris GmbH
- Current Assignee: Translate Bio, Inc.,Ethris GmbH
- Current Assignee Address: US MA Lexington DE Martinsried
- Agency: Proskauer Rose LLP
- Agent Fangli Chen; Julio J. Mendez
- International Application: PCT/US2013/044771 WO 20130607
- International Announcement: WO2013/185069 WO 20131212
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K9/00 ; C12N15/88 ; A61K31/7088 ; A61M15/00 ; A61M16/14 ; A61K48/00
Abstract:
Compositions comprising mRNA formulated for pulmonary administration and related methods for delivery of the mRNA and/or encoded protein to a non-lung cell or tissue. The compositions and methods may be used to prevent or ameliorate the symptoms of diseases associated with the mRNA encoded protein.
Public/Granted literature
- US20150157565A1 PULMONARY DELIVERY OF MRNA TO NON-LUNG TARGET CELLS Public/Granted day:2015-06-11
Information query
