An anti-malware application detects and remediates ransomware. The anti-malware application monitors processes executing on a computing device and detects that a process is opening a file for editing. A portion of the original file is saved prior to being edited by the process. Once the edited file is saved, the anti-malware application compares a portion of the edited file to the portion of the original file to determine if the edited file is encrypted. The anti-malware application may determine the process is associated with ransomware based on whether the edited file is encrypted.