A multi-projectile launcher capable of firing less-lethal 40 mm rounds or high explosive 40 mm rounds (i.e., HE Grenades) can be attached to robots, drones, vehicles and stationary structures. The robot/drone multi-projectile launcher is remote controlled and capable of 360 degree horizontal rotation as well as vertical panning, and is able to quickly turn and acquire targets. A solenoid controlled firing system for each barrel includes a firing pin, trigger lever and striker, as well as a lockout bar and striker seer to prevent accidental firing (e.g., from impact or sudden jolt). Target acquisition systems include an infrared laser system, a standard red laser system, and an optic targeting system that is monitored through an onboard camera. A wireless network access device allows for remote viewing of live-feed camera images (still frame and video) and control of the optic targeting system, as well as the launcher articulation and firing.