Charging handles having a mechanical advantage separator for separating an end of the charging handle from a portion of a firearm are disclosed. Specifically, charging handles having a simple machine, such as a lever, are disclosed. Advantageously, the simple machine can multiply the force applied by a user on the charging handle. Additionally, in at least some instances, the simple machine will actuate a charging handle latch so as to disengage the charging handle latch from a receiver of the firearm.