Invention Grant
- Patent Title: Reprogramming T cells and hematopoietic cells
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Application No.: US15498172Application Date: 2017-04-26
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Publication No.: US10221396B2Publication Date: 2019-03-05
- Inventor: Matthew Brown , Elizabeth Rondon Dominguez , Randy Learish , Emile Nuwaysir , Deepika Rajesh , Amanda Mack
- Applicant: Cellular Dynamics International, Inc.
- Applicant Address: US WI Madison
- Assignee: FUJIFILM Cellular Dynamics, Inc.
- Current Assignee: FUJIFILM Cellular Dynamics, Inc.
- Current Assignee Address: US WI Madison
- Agency: Parker Highlander PLLC
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N15/00 ; C12N5/074 ; C12N15/85 ; C12N15/86
Abstract:
Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from CD34+ hematopoietic cells, such as human CD34+ blood progenitor cells, or T cells. Various iPS cell lines are also provided. In certain embodiments, the invention provides novel induced pluripotent stem cells with a genome comprising genetic rearrangement of T cell receptors.
Public/Granted literature
- US20170226484A1 REPROGRAMMING T CELLS AND HEMATOPOIETIC CELLS Public/Granted day:2017-08-10
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