The invention provides an AMOLED pixel driver circuit and pixel driving method. The AMOLED pixel driver circuit has a 6T2C structure, comprising a first thin film transistor (TFT) (T1), a second TFT (T2) forming mirror relation with the first TFT (T1), a third TFT (T3), a fourth TFT (T4), a fifth TFT (T5), a sixth TFT (T6), a first capacitor (C1), a second capacitor (C2) and an organic light-emitting diode (OLED) (D1), and receiving a first scan signal (Scant), a second scan signal (Scan2), a third scan signal (Scan3), a data signal (Data), and a predefined voltage (Vpre). The circuit can effectively compensate the threshold voltages of the driving TFT and the OLED, simplify the data signal, stabilize the current flowing through the OLED to ensure uniform light-emission of the OLED and improve display quality.