Invention Grant
- Patent Title: Cancer stem cell vaccination and treatment
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Application No.: US14437064Application Date: 2013-10-24
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Publication No.: US10173074B2Publication Date: 2019-01-08
- Inventor: Qiao Li
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Harbor
- Assignee: The Regents of The University of Michigan
- Current Assignee: The Regents of The University of Michigan
- Current Assignee Address: US MI Ann Harbor
- Agency: Casimir Jones, S.C.
- Agent Jason R. Bond
- International Application: PCT/US2013/066578 WO 20131024
- International Announcement: WO2014/066615 WO 20140501
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61N5/10 ; A61K39/00 ; A61K45/06
Abstract:
The present invention relates to methods, systems, and compositions for treating and preventing cancer in a subject with the combination of radiation therapy and antigen presenting cells that have been exposed cancer stem cells or a portion thereof. In certain embodiments, the antigen presenting cells are dendritic cells that have been pulsed with ALDHhigh cancer stem cells.
Public/Granted literature
- US20150265848A1 CANCER STEM CELL VACCINATION AND TREATMENT Public/Granted day:2015-09-24
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