A mobile device and an eye-protection control method thereof are provided. The mobile device includes a display screen, an image capture unit, and a processer. The display screen is for displaying information. The image capture unit is for capturing a first image. The processer is coupled to the image capture unit to obtain the first image. The processer performs a human face detection to the first image to judge whether the first image has a human face information of a user. The processer counts a plurality of time periods when the first image has the human face information and adds up the time periods to a cumulative time, and the processer judges whether to perform an eye-protection operation through the cumulative time and a time threshold. Accordingly, the mobile device can remind the user to protect eyes and avoid overuse of the eyes.