The present invention relates to multi-user analytical system and corresponding device and method. The device includes an interception module configured to intercept a user's request for a first core object, wherein the first core object belongs to core object; a transformation module configured to create, in response to the request being a creation request, the first core object specific to the user; a mapping module configured to interpret, in response to the request being a non-creation request, the request as a request for the first core object specific to the user. The present invention also includes an isolation method for the multi-user analytical system. The technical solutions provided in the present invention can effectively enable multiple users to share physical resources in the analytical system, and the users are isolated from each other in a substantially transparent way.