A method for performing renal therapy at a home or dwelling of a patient using a renal therapy machine includes electronically retrieving a doctor's prescription for renal therapy and based on the doctor's prescription, enabling electronic selection of supplies, including a dialyzer, at a first location other than the patient's home or dwelling by a person other than the patient. The method further includes electronically initiating a sending of the supplies and the renal therapy machine to the patient's home or dwelling.