Invention Grant
- Patent Title: Compositions and methods for adjoining type I and type II extracellular domains as heterologous chimeric proteins
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Application No.: US15804533Application Date: 2017-11-06
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Publication No.: US10086042B2Publication Date: 2018-10-02
- Inventor: Taylor Schreiber , George Fromm , Suresh De Silva , Neal Schilling
- Applicant: Heat Biologics, Inc.
- Applicant Address: US NC Durham
- Assignee: Heat Biologics, Inc.
- Current Assignee: Heat Biologics, Inc.
- Current Assignee Address: US NC Durham
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: A61K38/17
- IPC: A61K38/17 ; C07K14/00 ; C07K19/00 ; A61K38/00
Abstract:
The present invention relates to, inter alia, compositions and methods, including chimeric proteins that find use in the treatment of disease, such as immunotherapies for cancer and autoimmunity. In part, the invention provides, in various embodiments, fusions of extracellular domains of transmembrane proteins that can have stimulatory or inhibitory effects.
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