Invention Grant
- Patent Title: Methods for treating and preventing cardiomyopathy with a fusion protein of tafazzin and a cellular permeability peptide
-
Application No.: US15528012Application Date: 2015-12-11
-
Publication No.: US10086040B2Publication Date: 2018-10-02
- Inventor: Michael T. Chin , Wei-Ming Chien , Ana Dinca
- Applicant: University of Washington
- Applicant Address: US WA Seattle
- Assignee: University of Washington
- Current Assignee: University of Washington
- Current Assignee Address: US WA Seattle
- Agency: Stoel Rives LLP
- Agent Zhi-Xiang (Alex) Oh
- International Application: PCT/US2015/065235 WO 20151211
- International Announcement: WO2016/094791 WO 20160616
- Main IPC: A61K38/45
- IPC: A61K38/45 ; A61P9/04 ; C07K14/47 ; A61K38/17 ; A61K38/16 ; A61K38/18 ; A61P9/00 ; C07K19/00 ; C07K7/08 ; C07K7/06
Abstract:
Methods for treating patients having a cardiomyopathy are provided. Additionally, methods for prophylactically treating patients at risk of developing a cardiomyopathy are provided. Methods for treating patients having, or at risk of developing, a cardiomyopathy may comprise administering a fusion protein including a tafazzin peptide and a cellular permeability peptide to the patient. Further, the tafazzin peptide may be coupled to the cellular permeability peptide by a polypeptide linker.
Public/Granted literature
- US20170360886A1 METHODS FOR TREATING AND PREVENTING CARDIOMYOPATHY Public/Granted day:2017-12-21
Information query
IPC分类:
