Composite bone grafts and methods for producing the same
Abstract:
The present disclosure is directed to composite bone grafts and to methods for providing such grafts for orthopedic and other surgical uses in a subject in need thereof. In some embodiments, the present disclosure provides a method for producing a composite bone graft, the method comprising, for example, the steps of: (i) selecting at least one donor site on at least one subject; (ii) removing at least one piece of bone, comprising cortical bone, from the at least one donor site; (iii) machining the at least one piece of bone to produce at least two bone components, each having a surface comprising at least one of a protuberance and a recess thereon; and (iv) joining the at least two machined bone components to produce a composite bone graft.
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