Invention Grant
- Patent Title: Dual probe assay for the detection of HCV
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Application No.: US15292570Application Date: 2016-10-13
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Publication No.: US10041134B2Publication Date: 2018-08-07
- Inventor: Frank Bergmann , Dorothea Sizmann , Heike Zitzer
- Applicant: Roche Molecular Systems, Inc.
- Applicant Address: US CA Pleasanton
- Assignee: Roche Molecular Systems, Inc.
- Current Assignee: Roche Molecular Systems, Inc.
- Current Assignee Address: US CA Pleasanton
- Agent David J. Chang; Eric Grant Lee
- Priority: EP12188990 20121018
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/70 ; C12Q1/6816 ; C07H21/04

Abstract:
The present invention relates to a method for amplifying and detecting a target nucleic acid of HCV in a sample, wherein an amplification of the nucleic acids in said sample is carried out. This amplification involves a polymerase, primers for generating an amplicon and at least two detectable probes specific for different sequence portions of said amplicon. Detection of the obtained amplicon is brought about by detecting hybridization of the probes mentioned above to said different sequence portions of the amplicon.The invention further provides reaction mixtures and kits for amplifying and detecting a target nucleic acid of HCV involving the use of at least two detectable probes specific for different sequence portions of an amplicon.
Public/Granted literature
- US20170088907A1 DUAL PROBE ASSAY FOR THE DETECTION OF HCV Public/Granted day:2017-03-30
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