- Patent Title: Cell-type specific aptamer-siRNA delivery system for HIV-1 therapy
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Application No.: US15362168Application Date: 2016-11-28
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Publication No.: US10041071B2Publication Date: 2018-08-07
- Inventor: John J. Rossi , Jiehua Zhou
- Applicant: City of Hope
- Applicant Address: US CA Duarte
- Assignee: City of Hope
- Current Assignee: City of Hope
- Current Assignee Address: US CA Duarte
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C12N15/115
Abstract:
The present invention relates to compositions and methods for delivery of siRNA to specific cells or tissue. More particularly, the present invention relates to compositions and methods for cell type-specific delivery of anti-HIV siRNAs via fusion to an anti-gp120 aptamer.
Public/Granted literature
- US20170073684A1 CELL-TYPE SPECIFIC APTAMER-siRNA DELIVERY SYSTEM FOR HIV-1 THERAPY Public/Granted day:2017-03-16
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