Invention Grant
- Patent Title: Treatment of diseases associated with hepatic stellate cell activation using ammonia-lowering therapies
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Application No.: US15527999Application Date: 2015-11-23
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Publication No.: US10039735B2Publication Date: 2018-08-07
- Inventor: Rajiv Jalan , Rajeshwar Prosad Mookerjee , Krista Rombouts , Fausto Andreola , Francesco De Chiara , Karen Louise Thomsen
- Applicant: UCL Business PLC
- Applicant Address: GB London
- Assignee: UCL BUSINESS PLC
- Current Assignee: UCL BUSINESS PLC
- Current Assignee Address: GB London
- Agency: Knobbe Martens Olson & Bear LLP
- International Application: PCT/US2015/062223 WO 20151123
- International Announcement: WO2016/085887 WO 20160602
- Main IPC: A61K31/216
- IPC: A61K31/216 ; A61K9/00 ; A61K31/198 ; A61K31/192
Abstract:
Disclosed herein are methods of preventing, treating, and delaying the onset or progression of diseases associated with hepatic stellate cells (HSCs), such as non-alcoholic fatty liver disease (NAFLD), fibrosis, and liver cancer, using ammonia-lowering therapies.
Public/Granted literature
- US20170354627A1 TREATMENT OF DISEASES ASSOCIATED WITH HEPATIC STELLATE CELL ACTIVATION USING AMMONIA-LOWERING THERAPIES Public/Granted day:2017-12-14
Information query
