Invention Grant
- Patent Title: 7-hydroxy cannabidiol (7-OH-CBD) for use in the treatment of non-alcoholic fatty liver disease (NAFLD)
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Application No.: US15321778Application Date: 2015-06-29
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Publication No.: US10039724B2Publication Date: 2018-08-07
- Inventor: Colin Stott , Marnie Duncan , Vincenzo Di Marzo , Cristoforo Silvestri , Andrea Martella
- Applicant: GW Pharma Limited
- Applicant Address: GB Cambridge
- Assignee: GW Research Limited
- Current Assignee: GW Research Limited
- Current Assignee Address: GB Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: GB1411467.2 20140627
- International Application: PCT/GB2015/051893 WO 20150629
- International Announcement: WO2015/198077 WO 20151230
- Main IPC: A61K31/05
- IPC: A61K31/05

Abstract:
The liver plays a key role in regulating total body energy homeostasis and its ability to do so is greatly affected by the occurrence of pathological conditions such as hepatosteatosis or non-alcoholic fatty liver disease (NAFLD), which contributes to hepatic insulin resistance and potentially end-stage liver disease-related mortality. Triglyceride accumulation in hepatocytes of steatotic livers results from the incorporation of plasma free fatty acids as well as de novo fat synthesis. The present invention relates to the use of 7-hydroxy-cannabidiol (7-OH-CBD) in the treatment of non-alcoholic fatty liver disease (NAFLD). Treatment of NAFLD involves lowering the triglyceride levels in a patient's blood stream.
Public/Granted literature
- US20170128385A1 7-HYDROXY CANNABIDIOL (7-OH-CBD) FOR USE IN THE TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) Public/Granted day:2017-05-11
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