Invention Grant
- Patent Title: Alternative splicing variant of OATP1B3 mRNA
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Application No.: US15226278Application Date: 2016-08-02
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Publication No.: US10011881B2Publication Date: 2018-07-03
- Inventor: Tomomi Furihata , Sayaka Matsumoto , Miki Nagai , Kan Chiba
- Applicant: National University Corporation Chiba University
- Applicant Address: JP Chiba
- Assignee: National University Corporation China University
- Current Assignee: National University Corporation China University
- Current Assignee Address: JP Chiba
- Agency: Cesari and McKenna, LLP
- Priority: JP2010-035166 20100219; JP2011-032501 20110217
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12Q1/68 ; C12Q1/6886 ; C07K14/47 ; G01N33/50 ; A61K39/00

Abstract:
[PROBLEM TO BE SOLVED]An object of the present invention is to provide a novel tumor marker and use thereof. In more detail, the present invention provides a novel tumor marker, a method for measuring said tumor marker and a measurement kit, a method for detecting cancer using the same, a kit for detecting cancer, a method for screening a preventive and/or therapeutic agent for cancer, as well as a medicament such as cancer vaccine.[SOLUTION]According to the present invention, a method for measuring an alternative splicing variant of OATP1B3 mRNA in a sample to be examined is provided. Said measurement method comprises measuring mRNA comprising a nucleotide sequence represented by SEQ ID NO: 1 in the sequence listing table in a sample to be examined isolated from living organism with differentiation from a mRNA comprising a nucleotide sequence represented by SEQ ID NO: 2. Said measurement method is useful for detecting cancer or screening a preventive and/or therapeutic agent.
Public/Granted literature
- US20160333426A1 NOVEL ALTERNATIVE SPLICING VARIANT OF OATP1B3 mRNA Public/Granted day:2016-11-17
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